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Found 2 Enz. Inhib. hit(s) with Target = 'Estrogen receptor [307-554]' and Ligand = 'BDBM300991'
TargetEstrogen receptor [307-554](Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM300991(6-((6S,8R)-7- ((1- fluorocyclo- propyl)methyl)-8- ...)
Affinity DataIC50:  5nMAssay Description:The assay was performed as follows with all reagent additions carried out using the Beckman Coulter BioRAPTR FRD microfluidic workstation:1. Acoustic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor [307-554](Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM300991(6-((6S,8R)-7- ((1- fluorocyclo- propyl)methyl)-8- ...)
Affinity DataIC50:  1.60E+4nMAssay Description:ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent