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Found 2 Enz. Inhib. hit(s) with Target = 'Eukaryotic initiation factor 4A-I' and Ligand = 'BDBM50388144'
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Boston University

Curated by ChEMBL
LigandPNGBDBM50388144(CHEMBL2058177)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of eIF4A1-mediated protein synthesis in human BJAB cells assessed as inhibition of [35S]Met incorporation after 72 hr by scintillation cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Boston University

Curated by ChEMBL
LigandPNGBDBM50388144(CHEMBL2058177)
Affinity DataIC50:  20nMAssay Description:Inhibition of eIF4A1-mediated protein synthesis in human BJAB cells assessed as inhibition of [35S]Met incorporation after 1 hr by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed