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Found 2 Enz. Inhib. hit(s) with Target = 'Eukaryotic initiation factor 4A-I' and Ligand = 'BDBM50576670'
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Effector Therapeutics

Curated by ChEMBL
LigandPNGBDBM50576670(CHEMBL4864162)
Affinity DataIC50:  5nMAssay Description:Inhibition of eIF4A (unknown origin) assessed as inhibition of translation of RNA featuring highly structured 5'-UTR of c-MycMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic initiation factor 4A-I(Homo sapiens (Human))
Effector Therapeutics

Curated by ChEMBL
LigandPNGBDBM50576670(CHEMBL4864162)
Affinity DataIC50:  21nMAssay Description:Inhibition of eIF4A (unknown origin) assessed as inhibition of translation of RNA featuring short 5'-UTR of tubulinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed