Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Eukaryotic translation initiation factor 4E' and Ligand = 'BDBM50294220'
TargetEukaryotic translation initiation factor 4E(Rabbit)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50294220(2-amino-9-[(2R,3R,4S,5R)-5-{[({[({[(2R,3S,4R,5R)-5...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of m7,3'-O-GpppG-c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Rabbit)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50294220(2-amino-9-[(2R,3R,4S,5R)-5-{[({[({[(2R,3S,4R,5R)-5...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Rabbit)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50294220(2-amino-9-[(2R,3R,4S,5R)-5-{[({[({[(2R,3S,4R,5R)-5...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate pre-incubated for 60 mins prior to mRNA addition by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Rabbit)
University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50294220(2-amino-9-[(2R,3R,4S,5R)-5-{[({[({[(2R,3S,4R,5R)-5...)
Affinity DataKi:  1.71E+4nMAssay Description:Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of rabbit beta-glo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed