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Found 3 Enz. Inhib. hit(s) with Target = 'Eukaryotic translation initiation factor 4E' and Ligand = 'BDBM50565476'
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50565476(CHEMBL4780117)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of recombinant human 10His-tagged eIF4E expressed in Escherichia coli BL21 (DE3) cells by catalytic enzyme-linked click chemistry assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50565476(CHEMBL4780117)
Affinity DataKd:  2.20nMAssay Description:Binding affinity to recombinant human 10His-tagged eIF4E expressed in Escherichia coli BL21 (DE3) cells assessed as binding constant by surface plasm...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50565476(CHEMBL4780117)
Affinity DataKon:  0.00690M-1s-1Assay Description:Binding affinity to recombinant human 10His-tagged eIF4E expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by surface ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed