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Found 4 Enz. Inhib. hit(s) with Target = 'Farnesyl diphosphate synthase' and Ligand = 'BDBM50341914'
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341914(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50:  93nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341914(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50:  93nMAssay Description:Inhibition of Toxoplasma gondii FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341914(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50:  810nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341914(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50:  811nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed