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Found 3 Enz. Inhib. hit(s) with Target = 'Farnesyl pyrophosphate synthase' and Ligand = 'BDBM36511'
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM36511(5-((2-Carboxy-1H-benzo[g]indol-1-yl)methyl)isoxazo...)
Affinity DataIC50:  80nMpH: 7.4 T: 2°CAssay Description:A biophysical assay using NMR spectroscopy to identify fragments with higher binding affinity to human recombinant FPPS.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM36511(5-((2-Carboxy-1H-benzo[g]indol-1-yl)methyl)isoxazo...)
Affinity DataIC50:  80nMAssay Description:Cardioselectivity for the beta-1 adrenergic receptor was determined against isoprenaline (antagonism) in isolated rat atriaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM36511(5-((2-Carboxy-1H-benzo[g]indol-1-yl)methyl)isoxazo...)
Affinity DataIC50:  80nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed