Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with Target = 'Farnesyl pyrophosphate synthase' and Ligand = 'BDBM50432306'
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50432306(CHEMBL2347862)
Affinity DataIC50:  22nMAssay Description:Allosteric inhibition of human recombinant FPPS using GPP and [3H]IPP as substrate incubated with enzyme for 10 mins prior to substrate addition by l...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50432306(CHEMBL2347862)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant FPPS using GPP/[3H]IPP as substrate incubated for 10 mins prior to substrate addition measured after 8 mins by scinti...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50432306(CHEMBL2347862)
Affinity DataIC50:  200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50432306(CHEMBL2347862)
Affinity DataIC50:  390nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged FPPS transfected in Escherichia coli BL21 (DE3) cells using GPP and [3H]-IPP as substrate incu...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50432306(CHEMBL2347862)
Affinity DataIC50:  390nMAssay Description:Inhibition of human recombinant FPPS using GPP/[3H]IPP as substrate incubated for 10 mins prior to substrate addition by scintillation counting analy...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50432306(CHEMBL2347862)
Affinity DataKd:  3.20E+3nMAssay Description:Binding affinity to human FPPS by isothermal titration colorimetry in absence of Mg2+ ionsMore data for this Ligand-Target Pair