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Found
1
Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' and Ligand = 'BDBM413527'
Target
Fatty acid synthase
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM413527
((R)-1-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)me...)
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Affinity Data
IC50: 42.7nM
Assay Description:
In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...
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Target Info
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Reactome pathway
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