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Found 11 Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM16673'
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of FGFR1 (unknown origin) incubated for 1 hr assessed as luminescence changes using ATP by ADP-Glo Kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  580nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  580nMAssay Description:Inhibition of FGFR-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  580nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  670nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  670nMAssay Description:Inhibition of FGFR-1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataKd:  2.80E+3nMAssay Description:Binding affinity to FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataKd:  2.80E+3nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataKd:  2.80E+3nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataKd:  2.80E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssayDrugBank

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataKd:  2.50E+3nMAssay Description:Average Binding Constant for FGFR1; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank