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Found 8 Enz. Inhib. hit(s) with Target = 'Focal adhesion kinase 1' and Ligand = 'BDBM418817'
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of recombinant FAK (unknown origin) by radiometric kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human recombinant FAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)
Affinity DataIC50:  0.630nMAssay Description:Inhibition of FAK (unknown origin) using Fluorescein-Poly GAT as substrate incubated for 30 mins and measured after 60 mins by Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)
Affinity DataIC50: <1nMAssay Description:Inhibition of human Focal adhesion kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of GST-FAK catalytic domain region (411-686) (unknown origin) expressed in baculovirus infected Sf9 cells by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human recombinant FAK using poly[Glu:Tyr] (4:1) substrate in presence of 10 mM ATP and [gamma33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM418817(N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed