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Found 4 Enz. Inhib. hit(s) with Target = 'Free fatty acid receptor 2' and Ligand = 'BDBM50305974'
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305974((S)-2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)bu...)
Affinity DataIC50:  700nMAssay Description:Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Mus musculus)
Ogeda

Curated by ChEMBL
LigandPNGBDBM50305974((S)-2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)bu...)
Affinity DataEC50:  158nMAssay Description:Agonist activity at mouse FFA2R expressed in CHOK1 cells assessed as induction of GTPgamma35S binding preincubated for 15 mins followed by GTPgamma35...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305974((S)-2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)bu...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human FFA2R expressed in CHOK1 cells assessed as induction of GTPgamma35S binding preincubated for 15 mins followed by GTPgamma35...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50305974((S)-2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)bu...)
Affinity DataEC50:  417nMAssay Description:Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed