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Found 4 Enz. Inhib. hit(s) with Target = 'Fructose-1,6-bisphosphatase 1' and Ligand = 'BDBM4626'
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM4626(Anilinoquinazoline deriv. 9 | CHEMBL301018 | N-(3-...)
Affinity DataIC50:  290nMAssay Description:Concentration required to inhibit the human liver recombinant fructose-1,6-bisphosphatase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM4626(Anilinoquinazoline deriv. 9 | CHEMBL301018 | N-(3-...)
Affinity DataIC50:  290nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFructose-1,6-bisphosphatase 1(Sus scrofa (Pig))
Pfizer

Curated by ChEMBL
LigandPNGBDBM4626(Anilinoquinazoline deriv. 9 | CHEMBL301018 | N-(3-...)
Affinity DataIC50:  340nMAssay Description:Compound was evaluated for its concentration required to inhibit the porcine kidney F16BPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM4626(Anilinoquinazoline deriv. 9 | CHEMBL301018 | N-(3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was evaluated for its concentration required to inhibit the rat liver F16BPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed