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Found 5 Enz. Inhib. hit(s) with Target = 'Fructose-1,6-bisphosphatase 1' and Ligand = 'BDBM50316379'
TargetFructose-1,6-bisphosphatase 1(Sus scrofa (Pig))
Boston College

Curated by ChEMBL
LigandPNGBDBM50316379(1,1'-(1,3,7,9-Tetrahydroxydibenzofuran-2,6-diyl)bi...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of pig kidney fructose-1,6-bisphosphatase expressed in Escherichia coli BL21 (DE3) assessed as reduction of NADP+ to NADPH by phosphogluco...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Sus scrofa (Pig))
Boston College

Curated by ChEMBL
LigandPNGBDBM50316379(1,1'-(1,3,7,9-Tetrahydroxydibenzofuran-2,6-diyl)bi...)
Affinity DataIC50:  5.00E+3nMpH: 7.5Assay Description:FBPase activity was measured spectrophotometrically by employing the coupling enzymes phosphoglucose isomerase and glucose-6-phosphate dehydrogenase....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50316379(1,1'-(1,3,7,9-Tetrahydroxydibenzofuran-2,6-diyl)bi...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human liver FBPase by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50316379(1,1'-(1,3,7,9-Tetrahydroxydibenzofuran-2,6-diyl)bi...)
Affinity DataIC50:  6.00E+3nMpH: 7.5Assay Description:FBPase activity was measured spectrophotometrically by employing the coupling enzymes phosphoglucose isomerase and glucose-6-phosphate dehydrogenase....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50316379(1,1'-(1,3,7,9-Tetrahydroxydibenzofuran-2,6-diyl)bi...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human liver fructose-1,6-bisphosphatase expressed in Escherichia coli BL21 (DE3) assessed as reduction of NADP+ to NADPH by phosphogluc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed