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Found 2 Enz. Inhib. hit(s) with Target = 'G-protein coupled bile acid receptor 1' and Ligand = 'BDBM50233498'
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50233498(CHEMBL4080612)
Affinity DataEC50:  125nMAssay Description:Agonist activity at TGR5 in mouse STC1 cells assessed as increase in cAMP accumulation after 40 mins by mass spectrometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50233498(CHEMBL4080612)
Affinity DataEC50:  1.25E+4nMAssay Description:Agonist activity at TGR5 in human NCI-H716 cells assessed as increase in cAMP accumulation after 40 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed