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Found 5 Enz. Inhib. hit(s) with Target = 'G-protein coupled receptor 35' and Ligand = 'BDBM50259839'
TargetG-protein coupled receptor 35(Homo sapiens (Human))TBA
LigandPNGBDBM50259839(CHEMBL4100677)
Affinity DataKi:  51nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))TBA
LigandPNGBDBM50259839(CHEMBL4100677)
Affinity DataIC50:  8.60nMAssay Description:Agonist activity at TEV protease cleavage site linked GAL4-VP16-fused GPR35 in human Tango GPR35-bla U2OS cells assessed as induction of TEV protease...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))TBA
LigandPNGBDBM50259839(CHEMBL4100677)
Affinity DataEC50:  3nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells incubated for 1 hr by DMR assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))TBA
LigandPNGBDBM50259839(CHEMBL4100677)
Affinity DataEC50:  197nMAssay Description:Agonist activity at TEV protease cleavage site linked GAL4-VP16-fused GPR35 in human Tango GPR35-bla U2OS cells assessed as induction of TEV protease...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 35(Homo sapiens (Human))TBA
LigandPNGBDBM50259839(CHEMBL4100677)
Affinity DataEC50:  5.80nMAssay Description:Agonist activity at GPR35 in human HT-29 cells by DMR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed