Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'GTPase KRas' and Ligand = 'BDBM50586345'
TargetGTPase KRas(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50586345(CHEMBL5090056)
Affinity DataIC50:  11nMAssay Description:Inhibition of KRAS G12C mutant (2 to 188 residues) (unknown origin) expressed in Escherichia coli assessed as inhibition of SOS mediated nucleotide e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGTPase KRas(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50586345(CHEMBL5090056)
Affinity DataEC50:  40nMAssay Description:Inhibition of KRAS G12C mutant in human HCC1171 cells assessed as effect on cell alkylation measured after 18 hrs by western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed