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Found 1 Enz. Inhib. hit(s) with Target = 'GTPase KRas [1-169,G12D]' and Ligand = 'BDBM550343'
TargetGTPase KRas [1-169,G12D]()
Amgen

US Patent
LigandPNGBDBM550343((M)-4-(4-Acryloyl-cis-3,5-dimethylpiperazin-1-yl)-...)
Affinity DataIC50:  53nMAssay Description:The following assay conditions were employed: Coupled Nucleotide Exchange Assay: Purified GDP-bound KRAS protein (aa 1-169), containing both G12C and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent