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Found 1 Enz. Inhib. hit(s) with Target = 'GTPase KRas [2-169,G12C]/Son of sevenless homolog 1 [564-1049]' and Ligand = 'BDBM581981'
TargetGTPase KRas [2-169,G12C]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Recurium Ip Holdings

WIPO
LigandPNGBDBM581981(WO2023287730, Compound P161-2.1)
Affinity DataIC50:  263nMAssay Description:Reaction buffer was prepared with 10 mM HEPES 7.4, 150 mM NaCl, 5 mM MgCl2, 1 mM DTT, 0.05% BSA, 0.0025% NP40, and 0.5% DMSO. Recombinant KRAS G12C p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed