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Found 3 Enz. Inhib. hit(s) with Target = 'GTPase KRas [G12D,Q61H]' and Ligand = 'BDBM485654'
TargetGTPase KRas [G12D,Q61H](Homo sapiens (Human))
Shy Therapeutics

US Patent
LigandPNGBDBM485654(US10940139, Example 02511 | US11000515, Compound T...)
Affinity DataIC50: <5.00E+3nMAssay Description:Buffer-I: 50 mM Tris, pH 7.5 150 mM NaCl (optional) 1 mM MgCl2 1 mM DTT. KRas G12D mutant protein was expressed as...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGTPase KRas [G12D,Q61H](Homo sapiens (Human))
Shy Therapeutics

US Patent
LigandPNGBDBM485654(US10940139, Example 02511 | US11000515, Compound T...)
Affinity DataIC50: <5.00E+3nMAssay Description:The following method was developed as specific assay for KRas G12D mutant protein.Buffer-I:50 mM Tris, pH 7.5150 mM NaCl (optional)1 mM MgCl21 mM DTT...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGTPase KRas [G12D,Q61H](Homo sapiens (Human))
Shy Therapeutics

US Patent
LigandPNGBDBM485654(US10940139, Example 02511 | US11000515, Compound T...)
Affinity DataIC50: <5.00E+3nMAssay Description:The following method was developed as specific assay for KRas G12D mutant protein.Buffer-I: 50 mM Tris, pH 7.5 150 mM NaCl (optional) ...More data for this Ligand-Target Pair
In DepthDetails US Patent