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Found 3 Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein' and Ligand = 'BDBM50461421'
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461421(CHEMBL3828596)
Affinity DataIC50:  1.70nMAssay Description:Binding affinity to CA-SP1 P373S/V370A double mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461421(CHEMBL3828596)
Affinity DataEC50:  0.680nMAssay Description:Binding affinity to CA-SP1 P373S mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation by measuring ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461421(CHEMBL3828596)
Affinity DataEC50:  2nMAssay Description:Binding affinity to CA-SP1 P373S mutant in HIV-1 subtype B NL4-3 infected in human MT2 cells assessed as inhibition of viral maturation by measuring ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed