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Found 1 Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C]' and Ligand = 'BDBM27604'
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM27604(2-{[4-(4-tert-butyl-2-chlorophenyl)-5-methyl-1H-py...)
Affinity DataIC50:  24nM EC50:  177nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation prox imity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value repres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed