Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with Target = 'Gamma-butyrobetaine dioxygenase' and Ligand = 'BDBM43362'
TargetGamma-butyrobetaine dioxygenase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM43362(MLS000069752 | N,N-dimethylcarbamodithioic acid (d...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of human BBOX pre-incubated for 25 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-butyrobetaine dioxygenase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM43362(MLS000069752 | N,N-dimethylcarbamodithioic acid (d...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of human BBOX pre-incubated for 20 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-butyrobetaine dioxygenase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM43362(MLS000069752 | N,N-dimethylcarbamodithioic acid (d...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human BBOX pre-incubated for 15 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-butyrobetaine dioxygenase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM43362(MLS000069752 | N,N-dimethylcarbamodithioic acid (d...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of human BBOX pre-incubated for 10 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-butyrobetaine dioxygenase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM43362(MLS000069752 | N,N-dimethylcarbamodithioic acid (d...)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of human BBOX pre-incubated for 1 min using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-butyrobetaine dioxygenase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM43362(MLS000069752 | N,N-dimethylcarbamodithioic acid (d...)
Affinity DataKd:  3.50E+4nMAssay Description:Binding affinity to human BBOX in presence of Fe(II) by tryptophan fluorescence quenching binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-butyrobetaine dioxygenase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM43362(MLS000069752 | N,N-dimethylcarbamodithioic acid (d...)
Affinity DataKd:  5.90E+4nMAssay Description:Binding affinity to human BBOX by tryptophan fluorescence quenching binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed