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Found 1 Enz. Inhib. hit(s) with Target = 'Gamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1' and Ligand = 'BDBM29011'
LigandPNGBDBM29011((2R)-2-[(4-chlorobenzene)(2,5-dichlorophenyl)sulfo...)
Affinity DataEC50:  0.270nMAssay Description:H4 human neuroglioma cells expressing beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced with the conditioned...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed