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Found 4 Enz. Inhib. hit(s) with Target = 'Genome polyprotein/Non-structural protein 4A' and Ligand = 'BDBM50120983'
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120983(CHEMBL115136 | [(S)-1-((4R,6R,6aS)-4-Acetyl-6-ethy...)
Affinity DataIC50:  1.47E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 hr preincubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120983(CHEMBL115136 | [(S)-1-((4R,6R,6aS)-4-Acetyl-6-ethy...)
Affinity DataIC50:  2.16E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120983(CHEMBL115136 | [(S)-1-((4R,6R,6aS)-4-Acetyl-6-ethy...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120983(CHEMBL115136 | [(S)-1-((4R,6R,6aS)-4-Acetyl-6-ethy...)
Affinity DataIC50:  4.47E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 h pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed