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Found 2 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM30506'
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Anadys Pharmaceuticals

LigandPNGBDBM30506(5,6-Dihydro-1H-pyridin-2-one, 4f)
Affinity DataIC50:  42nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme (NS5B H77 1a), RNA substrate, and [alpha-33P]GTP/GTP with inhibitor c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Anadys Pharmaceuticals

LigandPNGBDBM30506(5,6-Dihydro-1H-pyridin-2-one, 4f)
Affinity DataIC50:  57nM EC50:  74nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed