Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM35568'
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35568(1H-benzo[de]isoquinoline-1,3(2H)-dione, 17)
Affinity DataIC50:  130nM EC50:  2.00E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 2b (isolate HC-J8) (HCV...)
Irbm, Mrl Rome

LigandPNGBDBM35568(1H-benzo[de]isoquinoline-1,3(2H)-dione, 17)
Affinity DataIC50:  400nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed