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Found 4 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM50075604'
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075604((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  160nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075604((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  130nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075604((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  20nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075604((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  170nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed