Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM50495941'
TargetGenome polyprotein(Hepatitis C Virus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50495941(CHEMBL3349203)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50495941(CHEMBL3349203)
Affinity DataIC50:  0.270nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease D168Y mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50495941(CHEMBL3349203)
Affinity DataIC50:  0.420nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease A156T mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50495941(CHEMBL3349203)
Affinity DataIC50:  0.550nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS3/4A protease A156V mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed