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Found 5 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM50506842'
TargetGenome polyprotein(Zika virus)
Cnrs Umr7258

Curated by ChEMBL
LigandPNGBDBM50506842(CHEMBL3899268)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50506842(CHEMBL3899268)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of Zika virus MTase (4 to 278 residues) expressed in Escherichia coli T7 using GpppAC4 as substrate in presence of [3H]SAM incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Cnrs Umr7258

Curated by ChEMBL
LigandPNGBDBM50506842(CHEMBL3899268)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of WNV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50506842(CHEMBL3899268)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibition of Zika virus MTase (4 to 278 residues) expressed in Escherichia coli T7 using A27 RNA as substrate in presence of [3H]SAM incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus)
Cnrs Umr7258

Curated by ChEMBL
LigandPNGBDBM50506842(CHEMBL3899268)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of DENV3 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed