Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM50522790'
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50522790(CHEMBL3741422)
Affinity DataIC50:  400nMAssay Description:Inhibition of Dengue virus 2 NS2B-NS3 protease using Abz-Nle-Lys-Arg-Arg-Ser-Tyr(3-NO2)-NH2 as substrate preincubated with enzyme for 15 mins followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50522790(CHEMBL3741422)
Affinity DataIC50:  400nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease preincubated with protein for 15 mins followed by Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50522790(CHEMBL3741422)
Affinity DataIC50:  680nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Ty...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50522790(CHEMBL3741422)
Affinity DataIC50:  800nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease preincubated with protein for 15 mins followed by Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)-Tyr substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50522790(CHEMBL3741422)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of West Nile virus NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50522790(CHEMBL3741422)
Affinity DataEC50:  1.60E+4nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease transfected in human HeLa cells measured after 24 hrs by Renilla-luciferase reporter gene ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed