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Found 4 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM50525248'
TargetGenome polyprotein(Dengue virus 2)
Queensland University Of Technology

Curated by ChEMBL
LigandPNGBDBM50525248(CHEMBL4450411)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of GST-tagged DENV3 NS2B-NS3 serine protease expressed in Escherichia coli BL21Gold(DE3) using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Queensland University Of Technology

Curated by ChEMBL
LigandPNGBDBM50525248(CHEMBL4450411)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of DENV3 NS2B-NS3 protease using PhAc-Lys-Arg-Arg-AMC as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGenome polyprotein(Dengue virus 2)
Queensland University Of Technology

Curated by ChEMBL
LigandPNGBDBM50525248(CHEMBL4450411)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGenome polyprotein(Dengue virus 2)
Queensland University Of Technology

Curated by ChEMBL
LigandPNGBDBM50525248(CHEMBL4450411)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of His-tagged DENV2 NS2B-NS3 serine protease expressed in Escherichia coli BL21 using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed