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Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM514148'
Target
Genome polyprotein
(Dengue virus 2)
Janssen Pharmaceuticals
US Patent
Ligand
BDBM514148
(US11053196, Compound 2B)
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Affinity Data
EC50: 0.0780nM
Assay Description:
The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...
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