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Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM514204'
Target
Genome polyprotein
(Dengue virus 2)
Janssen Pharmaceuticals
US Patent
Ligand
BDBM514204
(US11053196, Compound 7B-D)
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Affinity Data
EC50: 16nM
Assay Description:
The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...
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