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Found 4 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM642920'
TargetGenome polyprotein(Norovirus Hu/GII.P4_GII.4/Minerva)
Emory University

US Patent
LigandPNGBDBM642920(US11859014, Compound 35)
Affinity DataKi:  465nMAssay Description:The ability of these compounds to inhibit the NoV, specifically Minerva virus protease catalytic Cys139 covalently (IC50 and Ki) was determined with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Norovirus Hu/GII.P4_GII.4/Minerva)
Emory University

US Patent
LigandPNGBDBM642920(US11859014, Compound 35)
Affinity DataKi:  858nMAssay Description:The ability of these compounds to inhibit the NoV, specifically Minerva virus protease catalytic Cys139 covalently (IC50 and Ki) was determined with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Norovirus Hu/GII.P4_GII.4/Minerva)
Emory University

US Patent
LigandPNGBDBM642920(US11859014, Compound 35)
Affinity DataIC50:  96nMAssay Description:The ability of these compounds to inhibit the NoV, specifically Minerva virus protease catalytic Cys139 covalently (IC50 and Ki) was determined with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Norovirus Hu/GII.P4_GII.4/Minerva)
Emory University

US Patent
LigandPNGBDBM642920(US11859014, Compound 35)
Affinity DataIC50:  167nMAssay Description:The ability of these compounds to inhibit the NoV, specifically Minerva virus protease catalytic Cys139 covalently (IC50 and Ki) was determined with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent