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Found 4 Enz. Inhib. hit(s) with Target = 'Geranylgeranyl pyrophosphate synthase' and Ligand = 'BDBM50151859'
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50151859(CHEMBL3775876)
Affinity DataIC50:  45nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) assessed as radiolabeled GGPP formation preincubated for 10 mins followed by addition of 10 uM FPP s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50151859(CHEMBL3775876)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) using FPP as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50151859(CHEMBL3775876)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) using FPP as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Iowa

Curated by ChEMBL
LigandPNGBDBM50151859(CHEMBL3775876)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) using FPP as substrate pretreated for 10 mins followed by substrate addition after 30 mins in presen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed