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Found 2 Enz. Inhib. hit(s) with Target = 'Glucagon receptor' and Ligand = 'BDBM50334476'
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334476(CHEMBL1644178 | trans-4-((5-(4-tert-butylcyclohexy...)
Affinity DataIC50:  63nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334476(CHEMBL1644178 | trans-4-((5-(4-tert-butylcyclohexy...)
Affinity DataIC50:  170nMAssay Description:Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed