Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Glucagon-like peptide 1 receptor' and Ligand = 'BDBM50393579'
TargetGlucagon-like peptide 1 receptor(Rattus norvegicus)
The National Center for Drug Screening

Curated by ChEMBL
LigandPNGBDBM50393579(CHEMBL2158415)
Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1C[C@]1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O
Show InChI InChI=1S/C28H28N2O8S/c1-27(2,3)38-26(35)29-18-10-7-16(8-11-18)23(31)30-28(25(33)34)15-19(28)17-9-12-20(21(14-17)36-4)37-24(32)22-6-5-13-39-22/h5-14,19H,15H2,1-4H3,(H,29,35)(H,30,31)(H,33,34)/t19-,28-/m1/s1
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Rattus norvegicus)
The National Center for Drug Screening

Curated by ChEMBL
LigandPNGBDBM50393579(CHEMBL2158415)
Show SMILES COc1cc(ccc1OC(=O)c1cccs1)[C@H]1C[C@]1(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)C(O)=O
Show InChI InChI=1S/C28H28N2O8S/c1-27(2,3)38-26(35)29-18-10-7-16(8-11-18)23(31)30-28(25(33)34)15-19(28)17-9-12-20(21(14-17)36-4)37-24(32)22-6-5-13-39-22/h5-14,19H,15H2,1-4H3,(H,29,35)(H,30,31)(H,33,34)/t19-,28-/m1/s1
Affinity DataEC50: >2.00E+4nMAssay Description:Agonist activity at rat GLP1R expressed in HEK293 cells assessed as stimulation of cAMP levels incubated for 6 hrs by multiple response element/cAMP ...More data for this Ligand-Target Pair