Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50334049'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334049(5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2...)
Affinity DataKi:  5.80nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334049(5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2...)
Affinity DataIC50:  13nMAssay Description:Transrepression activity at glucocorticoid receptor in TNFalpha/IL1beta-stimulated human HepG2 cells assessed as inhibition of NFkappaB-dependent E-s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334049(5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2...)
Affinity DataEC50:  235nMAssay Description:Agonist activity at glucocorticoid receptor in human HepG2 cells co-transfected with GRE assessed as transactivation activity by luciferase reporter ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed