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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) with Target = 'Glutamate receptor 1' and Ligand = 'BDBM426226'
Target
Glutamate receptor 1
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM426226
(5-[2-(4-Fluorophenyl)-7-(4-hydroxy-1-piperidyl)pyr...)
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Affinity Data
IC50: 0.200nM
Assay Description:
This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...
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Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
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Ligand Info
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US Patent
PDB
3D Structure (crystal)
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