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Found 7 Enz. Inhib. hit(s) with Target = 'Glutamate receptor 1' and Ligand = 'BDBM50128264'
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataKi:  130nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA1o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataKi:  130nMAssay Description:Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 1 (GluR1) expressed in Sf 9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataIC50:  220nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA receptor, using radioligand [3H]- AMPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataEC50:  4.10E+3nMAssay Description:Agonist activity at GluA1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataEC50:  4.70E+3nMAssay Description:Agonist activity at rat recombinant GluA1i expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Mus musculus)
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataEC50:  4.70E+3nMAssay Description:Effective concentration of compound was determined for electrophysiological properties on Ionotropic glutamate receptor AMPA 1 (GluR1) using rat cort...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataEC50:  4.70E+3nMAssay Description:Agonist activity at recombinant GluA1 receptor flip isoform expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed