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Found 4 Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1/2B' and Ligand = 'BDBM50149684'
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50149684(2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-oxo-N-(2-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50149684(2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-oxo-N-(2-...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity against NR1/NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50149684(2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-oxo-N-(2-...)
Affinity DataIC50:  6nMAssay Description:Displacement of [3H]-Ro-256981 from recombinant NR1/NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50149684(2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-oxo-N-(2-...)
Affinity DataIC50:  70nMAssay Description:Antagonist activity against NR1a/NR2B receptor transfected in human HEK293 cells assessed as inhibition of NMDA-induced Ca2+ influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed