Found 3 Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM198665'
Affinity DataKi: 1.40nM ΔG°: -54.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Binding affinity to GluN2B receptor in human cortexMore data for this Ligand-Target Pair