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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Glutaminase kidney isoform, mitochondrial [63-669]' and Ligand = 'BDBM387036'
TargetGlutaminase kidney isoform, mitochondrial [63-669](Human)
Astrazeneca

US Patent
LigandPNGBDBM387036(2-(4-fluoro-3-methoxy-phenyl)-N-[5-[[(3R)-1-(6-flu...)
Affinity DataIC50:  71.3nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetGlutaminase kidney isoform, mitochondrial [63-669](Human)
Astrazeneca

US Patent
LigandPNGBDBM387036(2-(4-fluoro-3-methoxy-phenyl)-N-[5-[[(3R)-1-(6-flu...)
Affinity DataIC50:  265nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent