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Found 4 Enz. Inhib. hit(s) with Target = 'Glycogen phosphorylase, liver form' and Ligand = 'BDBM35346'
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM35346((S)-5-chloro-N-(3-(4-fluorophenyl)-1-(4-hydroxypip...)
Affinity DataIC50:  205nMAssay Description:In vitro inhibitory activity against recombinant human liver glycogen phosphorylase a (rHLGPa) catalyzed release of phosphate from glucose-1-phosphat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM35346((S)-5-chloro-N-(3-(4-fluorophenyl)-1-(4-hydroxypip...)
Affinity DataIC50:  920nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM35346((S)-5-chloro-N-(3-(4-fluorophenyl)-1-(4-hydroxypip...)
Affinity DataIC50:  920nMpH: 6.8 T: 2°CAssay Description:The activity of recombinant human liver GPa in the forward direction was measured by monitoring the production of NADPH. Enzyme activity was assayed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM35346((S)-5-chloro-N-(3-(4-fluorophenyl)-1-(4-hydroxypip...)
Affinity DataIC50:  2.40E+3nMAssay Description:In vitro inhibition of pig liver Glycogen phosphorylase A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed