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Found 2 Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 alpha' and Ligand = 'BDBM188510'
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM188510((S)-4-(2-methoxyphenyl)-3,7,7-trimethyl-2,4,6,7,8,...)
Affinity DataIC50:  550nMAssay Description:A solution of 4× inhibitor (5 μL), 4× substrate/ATP-Metal solution (5 μL), and 2× Kinase solution (10 μL) was prepared with assay buff...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM188510((S)-4-(2-methoxyphenyl)-3,7,7-trimethyl-2,4,6,7,8,...)
Affinity DataIC50:  5.06E+3nMpH: 7.5 T: 2°CAssay Description:Purified GSK3beta was incubated with tested compounds in doses in the presence of 4.3 uM of ATP and 1.5uM peptide substrate (Peptide 15, Caliper, MA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed