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Found 5 Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM385337'
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM385337(US10287267, Compound 1024 | US10508099, Compound 1...)
Affinity DataEC50:  150nMAssay Description:Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM385337(US10287267, Compound 1024 | US10508099, Compound 1...)
Affinity DataEC50:  150nMAssay Description:Each compound is dissolved in DMSO as a 10 mM stock and used to prepare compound source plates. Serial dilution (1:3, 11-point dose-response curves f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM385337(US10287267, Compound 1024 | US10508099, Compound 1...)
Affinity DataEC50:  150nMAssay Description:The GSK3B kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies-a Divisio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM385337(US10287267, Compound 1024 | US10508099, Compound 1...)
Affinity DataEC50:  150nMAssay Description:The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM385337(US10287267, Compound 1024 | US10508099, Compound 1...)
Affinity DataEC50:  150nMAssay Description:GSK3B: This is a non-radioactive assay using fluorescence resonance energy transfer (FRET) between coumarin and fluorescein to detect kinase activity...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent