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Found 2 Enz. Inhib. hit(s) with Target = 'Heat shock factor protein 1' and Ligand = 'BDBM610358'
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM610358(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50:  14nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM610358(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50:  19nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent