Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha/90-beta' and Ligand = 'BDBM50150160'
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Conforma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50150160(Carbamic acid (4E,6Z,10E)-(8S,9S,12S,13R,14S,16R)-...)
Affinity DataIC50: 3nMAssay Description:Concentration of test compound required for inhibition of binding of rHsp90 in MCF-7 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Conforma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50150160(Carbamic acid (4E,6Z,10E)-(8S,9S,12S,13R,14S,16R)-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human epidermal growth factor 2 (Her-2) degradation in MCF-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Conforma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50150160(Carbamic acid (4E,6Z,10E)-(8S,9S,12S,13R,14S,16R)-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Concentration required to inhibit biotin-GM binding to recombinant heat shock protein 90(rHsp90)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Conforma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50150160(Carbamic acid (4E,6Z,10E)-(8S,9S,12S,13R,14S,16R)-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Concentration required to inhibit Bis-ANS activity by recombinant heat shock protein 90 (rHSP90) conformational assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed