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Found 4 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha/90-beta' and Ligand = 'BDBM50150162'
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Conforma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50150162(CHEMBL127088 | Carbamic acid (4E,6Z,10E)-(8S,9S,12...)
Affinity DataIC50:  12nMAssay Description:Concentration of test compound required for inhibition of binding of rHsp90 in MCF-7 cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Conforma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50150162(CHEMBL127088 | Carbamic acid (4E,6Z,10E)-(8S,9S,12...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human epidermal growth factor 2 (Her-2) degredation in MCF-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Conforma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50150162(CHEMBL127088 | Carbamic acid (4E,6Z,10E)-(8S,9S,12...)
Affinity DataIC50:  5.50E+3nMAssay Description:Concentration required to inhibit biotin-GM binding to recombinant heat shock protein 90(rHsp90)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Conforma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50150162(CHEMBL127088 | Carbamic acid (4E,6Z,10E)-(8S,9S,12...)
Affinity DataIC50:  5.80E+3nMAssay Description:Concentration required to inhbit Bis-ANS activity by recombinant heat shock protein 90 (rHSP90) conformational assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed